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Aminopurvalanol A, cyclin-dependent kinase inhibitor
ab145052 · 10 mg
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Catalog No: ab145052
Category: Biochemicals
Pack Size: 10 mg
Brand: abcam
Description
MW 403.9 Da, Purity >99 %. Potent, cell-permeable cyclin-dependent kinase inhibitor IC50 values are 33 cdk1/cyclin B , 33 cdk2/cyclin A , 28 cdk2/cyclin E and 20 nM cdk5/p35 . Inhibits ERK1 IC50 = 12.0 muM and ERK2 IC50 = 3.1 muM . Induces cell cycle arrest at G2/M phase IC50 = 1.25 muM . Shows apoptotic effects.
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