GENERAL CATALOGUE
AKT-IN-28
HY-174254 · 50 mg
MedChemExpress · Cat: HY-174254
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medchemexpress.com/akt-in-28.html
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Catalog No: HY-174254
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
AKT-IN-28 is an Akt allosteric inhibitor, a derivative of Shikonin HY-N0822 . AKT-IN-28 effectively binds to the allosteric site of Akt through hydrophobic and hydrogen interactions with Kd of 2.07??M. AKT-IN-28 significantly inhibits Akt activity, induces cell apoptosis, arrests cell cycle in G2/M phase, and suppresses proliferation, migration and metabolism of KRAS mutant colorectal cancer cells.
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