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Afatinib (BIBW 2992), Her2/ErbB 2 and EGFR kinase inhibitor
ab142018 · 10 mg
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Catalog No: ab142018
Category: Biochemicals
Pack Size: 10 mg
Brand: abcam
Description
MW 485.9 Da, Purity >98 %. Potent, irreversible Her2/ErbB 2 and EGFR kinase inhibitor IC50 values are 0.5, 0.4, 10 and 14 nM for EGFR wt , EGFR L858R , EGFR L858R/T790M and HER2 respectively . Shows antitumor effects in vivo. Orally active.
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