GENERAL CATALOGUE
Acid Ceramidase-IN-1
HY-141866 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-141866
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Catalog No: HY-141866
CAS No: 2415225-30-6
Category: Metabolic Enzyme Protease
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Acid Ceramidase-IN-1 is orally active and blood-brain barrier penetrant acid ceramidase AC, ASAH-1 inhibitor hAC IC50=0.166 ?M . Acid Ceramidase-IN-1 reduces AC activity, accumulates ceramide species Cer d18:0/16:0 , Cer d18:1/16:0 , and decreases sphingosine levels. Acid Ceramidase-IN-1 can be used for the study of severe neurological lysosomal storage diseases LSDs such as GaucherAAasAasAas disease GD and KrabbeAAasAasAas disease KD .
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