GENERAL CATALOGUE
A-86929
HY-171472 · 50 mg
MedChemExpress · Cat: HY-171472
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medchemexpress.com/a-86929.htmlCatalog No: HY-171472
CAS No: 171961-95-8
Category: GPCR G Protein
Pack Size: 50 mg
Brand: MedChemExpress
Description
A-86929 is a highly potent and selective dopamine D1 receptor agonist with a pKi value of 7.3. In the 6-OHDA HY-B1081 -induced unilateral nigrostriatal lesion rat model, A-86929 significantly induces rotational behavior. It also improves motor function in the MPTP HY-15608 -induced Parkinsons disease marmoset model. Additionally, A-86929 demonstrates potential therapeutic value in reducing cocaine-seeking behavior in rats and reversing Haloperidol HY-14538 -induced cognitive deficits in rhesus monkeys. A-86929 can be used for research in neurological disorders.
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