8-Azido-ADP disodium

Description

8-Azido-ADP disodium is a covalent-binding inhibitor of mitochondrial adenine nucleotide translocation. 8-Azido-ADP disodium causes irreversible inhibition of adenine nucleotide exchange in a light-dependent reaction. 8-Azido-ADP disodium inhibits the normal state 4 ? 3 transitions of mitochondrial respiration induced by ADP. 8-Azido-ADP disodium is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction CuAAc with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition SPAAC reactions with molecules containing DBCO or BCN groups.