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8(9)-EET
GENERAL CATALOGUE

8(9)-EET

HY-160431 · 1 mg

MedChemExpress · Cat: HY-160431

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medchemexpress.com/8-9-eet.html
Catalog No: HY-160431
CAS No: 82864-43-5
Category: Cell Cycle DNA Damage
Pack Size: 1 mg
Brand: MedChemExpress

Description

8 9 -EET is a major cytochrome P450 CYP450 metabolite in the renal cortex 1 2 . It activates PPAR? in HEK293 cells when used at a concentration of 1 ?M but inhibits NF-?B activity induced by IL-1? in a PPAR?-dependent and -independent fashion. It is also a substrate of COX-1 and COX-2, as measured by oxygen consumption and product formation assays when used at a concentration of 50 ?M .

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