

HY-160431 · 1 mg
MedChemExpress · Cat: HY-160431
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Manufacturer product page
medchemexpress.com/8-9-eet.html
Description
8 9 -EET is a major cytochrome P450 CYP450 metabolite in the renal cortex 1 2 . It activates PPAR? in HEK293 cells when used at a concentration of 1 ?M but inhibits NF-?B activity induced by IL-1? in a PPAR?-dependent and -independent fashion. It is also a substrate of COX-1 and COX-2, as measured by oxygen consumption and product formation assays when used at a concentration of 50 ?M .





