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7-Cl-O-Nec1, metabolically stable RIP1 inhibitor
ab221984 · 5 mg
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Catalog No: ab221984
Category: Biochemicals
Pack Size: 5 mg
Brand: abcam
Description
MW 277.7 Da, Purity >98 %. Necrostatin-1 ab141053 analog with superior selectivity and metabolic stability in blocking RIP1. No off-target inhibition of indolamine-2,3-deoxygenase IDO in contrast to Necrostatin-1. Higher activity in inhibiting necroptosis in Jurkat cells than Necrostatin-1 EC50 = 210 nM vs. EC50 = 490 nM .
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