GENERAL CATALOGUE
6PGD-IN-2
HY-175492 · 50 mg
MedChemExpress · Cat: HY-175492
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medchemexpress.com/6pgd-in-2.htmlCatalog No: HY-175492
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress
Description
6PGD-IN-2 is an uncompetitive 6-phosphogluconate dehydrogenase 6PGD inhibitor with an IC50 of 5.1 ?M. 6PGD-IN-2 disrupts 6PGD oligomerization in a substrate-dependent manner. 6PGD-IN-2 results in a decrease of NADPH and Ru-5-P production as well as DNA synthesis in A549 cells. 6PGD-IN-2 can used for the studies of non-small cell carcinoma and liver cancer.