GENERAL CATALOGUE
5MPN
HY-123981 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-123981
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medchemexpress.com/5mpn.html
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Catalog No: HY-123981
CAS No: 47208-82-2
Category: Metabolic Enzyme Protease
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
5MPN is a first-in-class, potent, orally active and selective 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 PFKFB4 inhibitor. 5MPN appears to be a competitive inhibitor of the F6P binding site Ki=8.6 ?M . 5MPN does not inhibit PFK-1 or PFKFB3. 5MPN targets the sugar metabolism of tumors and suppresses proliferation of multiple human cancer cell lines.
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