3,5-Diiodothyropropionic acid (Standard)

Description

3,5-Diiodothyropropionic acid Standard is the analytical standard of 3,5-Diiodothyropropionic acid. This product is intended for research and analytical applications. 3,5-Diiodothyropropionic acid is a thyroid hormone analog, induces ?-myosin heavy chain mRNA expression, binds to thyroid hormone receptor TR , with Ka of 2.40 and 4.06 M-1 for TR?1 and TR?1, respectively. 3,5-Diiodothyropropionic acid promotes angiogenesis in 3-D human dermal microvascular endothelial cell sprouting assay. 3,5-Diiodothyropropionic acid prevents myocardial arteriolar loss in thyroidectomized rats and enhances cardiac energy-generating capacity in postinfarction heart failure rats. 3,5-Diiodothyropropionic can be used in studies related to angiogenesis and heart failure.