GENERAL CATALOGUE
(1E)-CFI-400437 dihydrochloride
HY-132135 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-132135
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Catalog No: HY-132135
CAS No: 1247000-76-5
Category: Cell Cycle DNA Damage
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
1E -CFI-400437 dihydrochloride is a potent PLK4 IC50= 0.6 nM inhibitor and selective against other members of the PLK family 10 ?M. 1E -CFI-400437 dihydrochloride inhibits Aurora A, Aurora B, KDR and FLT-3 with IC50s of 0.37, 0.21, 0.48, and 0.18 ?M, respectively. Antiproliferative activity.
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