11-Ketodihydrotestosterone (Standard)

Description

11-Ketodihydrotestosterone Standard is the analytical standard of 11-Ketodihydrotestosterone. This product is intended for research and analytical applications. 11-Ketodihydrotestosterone 11-KDHT; 5?-Dihydro-11-keto testosterone is an endogenous steroid and a metabolite of 11?-Hydroxyandrostenedione. 11-Ketodihydrotestosterone is an active androgen and is also a potent androgen receptor AR agonist with a Ki of 20.4 nM and an EC50 of 1.35 nM for human AR. 11-Ketodihydrotestosterone drives gene regulation, protein expression and cell growth in androgen-dependent prostate cancer cells.